Over the past decade, a series of studies have found that physicians-in-training who work extended shifts are at increased risk of experiencing motor vehicle crashes, needlestick injuries, and medical errors. In response to public concerns and a request from Congress, the Institute of Medicine conducted an inquiry into the issue and concluded in 2009 that resident physicians should not work for more than 16 consecutive hours without sleep. They further recommended that the Centers for Medicare & Medicaid Services and the (...) Joint Commission work with the Accreditation Council for Graduate Medical Education to ensure effective enforcement of new work hour standards.The IOM's concerns with enforcement stem from well-documented non-compliance with the ACGME's 2003 work hour rules, and the ACGME's history of non-enforcement. In a nationwide cohort study, 84% of interns were found to violate the ACGME's 2003 standards in the year following their introduction. (shrink)

(2008). The Framework of Essences in Spinoza's Ethics. British Journal for the History of Philosophy: Vol. 16, No. 3, pp. 489-509. doi: 10.1080/09608780802200489.

Derk Pereboom has posed an empirical objection to agent-causal libertarianism: The best empirically confirmed scientific theories feature physical laws predicting no long-run deviations from fixed conditional frequencies that govern events. If agent-causal libertarianism were true, however, then it would be virtually certain, absent ‘wild coincidences’, that such long-run deviations would occur. So, current empirical evidence makes agent-causal libertarianism unlikely. This paper formulates Pereboom’s ‘Problem of Wild Coincidences’ as a five-step argument and considers two recent responses. Then, it offers a different (...) response: The Problem of Wild Coincidences does not show that current empirical evidence makes agent-causal libertarianism unlikely, even if all events are governed by physical laws featuring fixed long-run conditional frequencies and even if agents can ‘overrule’ normal physical laws. (shrink)

Tracing a path opened by an enigmatic reference in Reiner Schürmann’s dissertation to the symbol of water in James Baldwin’s, this essay follows the thinking of Schürmann and Baldwin to the tragic denial that perverts the ideals of the United States from the moment of its founding. Drawing on Schürmann’s imperative hermeneutics, we attend to Baldwin’s essays from the 1960s as they call white citizens of the United States to take on the “hideously difficult” task of achieving our identity as (...) a nation by facing our history and transforming ourselves as human beings. The symbols of water, fire, and love point us to new ways of existing rooted in practices of love—sensual releasement, ethical candor, and ethical imagination—that just might enable us to create a more perfect union. (shrink)

A $\Pi _{1}^{0}$ class is the set of paths through a computable tree. Given classes P and Q, P is Medvedev reducible to Q, P ≤M Q, if there is a computably continuous functional mapping Q into P. We look at the lattice formed by $\Pi _{1}^{0}$ subclasses of 2ω under this reduction. It is known that the degree of a splitting class of c.e. sets is non-branching. We further characterize non-branching degrees, providing two additional properties which guarantee non-branching: inseparable (...) and hyperinseparable. Our main result is to show that non-branching iff inseparable if hyperinseparable if homogeneous and that all unstated implications do not hold. We also show that inseparable and not hyperinseparable degrees are downward dense. (shrink)

In the Gorgias, Socrates claims to practice the true art of politics, but the peculiar politics he practices involves cultivating in each individual he encounters an erotic desire to live a life animated by the ideals of justice, beauty and the good. Socratic and Platonic Political Philosophy demonstrates that what Socrates sought to do with those he encountered, Platonic writing attempts to do with readers. Christopher P. Long's attentive readings of the Protagoras, Gorgias, Phaedo, Apology, and Phaedrus invite us (...) to cultivate the habits of thinking and responding that mark the practices of both Socratic and Platonic politics. Platonic political writing is here experienced in a new way as the contours of a politics of reading emerges in which the community of readers is called to consider how a commitment to speaking the truth and acting toward justice can enrich our lives together. (shrink)

. Human capabilities theory has emerged as an important framework for measuring whether various social systems promote human flourishing. The premise of this theory is that human beings share some nearly universal capabilities; what makes a human life fulfilling is the opportunity to exercise these capabilities. This essay proposes that the use of human capabilities theory can be expanded to assess whether a company has organized the work environment in such a way that allows workers to develop a variety of (...) human capabilities. This mode of analysis is put forward as a complement to the work of Mihaly Csikszentmihalyi, who has suggested that the key to promoting human well-being in the workplace is the maximization of flow experiences. (shrink)

Ontology has been traditionally guided by sophia, a form of knowledge directed toward that which is eternal, permanent, necessary. This tradition finds an important early expression in the philosophical ontology of Aristotle. Yet in the Nicomachean Ethics, Aristotle's intense concern to do justice to the world of finite contingency leads him to develop a mode of knowledge, phronsis, that implicitly challenges the hegemony of sophia and the economy of values on which it depends. Following in the tradition of the early (...) Heidegger's recognition of the ontological significance of Aristotle's Ethics and of Gadamer's appropriation of phronsis for hermeneutics, this article argues that an ontology guided by phronsis is preferable to one governed by sophia. Specifically, it suggests that by taking sophia as its paradigm, traditional philosophical ontology has historically been determined by a kind of knowledge that is incapable of critically considering the concrete historico-ethico-political conditions of its own deployment. This critique of sophia is accomplished by uncovering the economy of values that led Aristotle to privilege sophia over phronsis. It is intended to open up the possibility of developing an ontology of finite contingency based on phronsis. Such an ontology, because it is guided by and must remain responsible to the concrete individual with which it is engaged, would be ethical at its very core. (shrink)

Using a subliminal priming lexical decision task, the present research investigated whether individuals who show negative implicit evaluations of an ex-partner immediately after a break-up show superior post-break-up emotional adjustment. As expected, individuals whose reaction times indicated negative implicit evaluations of their ex-partner showed reduced depressive affect immediately after the break-up. Individuals who did not initiate their break-up demonstrated less negative implicit evaluations of their ex-partners as well as more depressive affect. Finally, increased negative implicit evaluations of ex-partners over a (...) one-month period were associated with corresponding improvements in adjustment. The findings demonstrate a critical role for implicit evaluations in post-break-up adjustment. (shrink)

For the mature Leibniz, a living being is a created substance composed of an infinitely complex organic body and a simple, immaterial soul. Soul and body do not interact directly, but rather their states correspond according to a harmony preestablished by God. I show that Leibniz’s theory faces challenges with respect to the question of whether substances need to possess knowledge of how they bring about their effects, and I argue that, to address these challenges, Leibniz turns to a concept (...) of “divine preformation” that he attributes to both soul and body. Insofar as divine preformation provides Leibniz with an explanation for how soul and body can both act without possessing explicit knowledge of what they are doing, it serves as a key tool for justifying the theory of preestablished harmony. (shrink)

In Plato’s Protagoras Alcibiades plays the role of Hermes, the ‘ambassador god,’ who helps lead Socrates’ conversation with Protagoras through a crisis of dialogue that threatens to destroy the community of education established by the dialogue itself. By tracing the moments when Alcibiades intervenes in the conversation, we are led to an understanding of Socratic politics as always concerned with the course of the life of an individual and the proper time in which it might be turned toward the question (...) of justice and the good. (shrink)

The subject of “the last pagans” or “the end of paganism” in the Greco-Roman world has interested scholars for over a century but begs the question “What is paganism?” Is the term usable as a tool of analysis? It originates from the Latin paganus, meaning “villager,” “rustic,” and reflects the way that Latin speakers viewed early Christianity as a phenomenon of the countryside, much as the English heathen, or German Heide, derives from a root meaning “heath.” Greek-speaking Christians, by contrast, (...) used a variety of terms, but their favored one was Hellene, which reflected the perception that their main opposition came from Greeks who remained faithful to their traditional culture and beliefs. Hence paganism, when used by a modern author, is implicitly one-sided and also obscures the very real gap in perception between Greek speakers and Latin speakers of antiquity. Accordingly, some recent authors have tried to replace pagan with polytheist, but the latter term has the disadvantage that many pagans tended toward monotheism, or to a modified monotheism that regarded one god as vastly superior to all others (“henotheism”). Heathen is similar in being an insider's term, current when Christianity was the default position of religious discourse, and now largely obsolete. It is best to retain the word pagan but to concede that it is merely a pis aller. (shrink)

Scholars often assume that Aristotle uses the terms morphē and eidos interchangeably. Translators of Aristotle's works rarely feel the need to carry the distinctionbetween these two Greek terms over into English. This article challenges the orthodox view that morphē and eidos are synonymous. Careful analysis of texts fromthe Categories, Physics, and Metaphysics in which these terms appear in close proximity reveals a fundamental tension of Aristotle's thinking concerning the being of natural beings. Morphē designates the form as inseparable from the (...) matter in which it inheres, while eidos, because it is more easily separated from matter, is the vocabulary used to determine form as the ontological principle of the composite individual. The tension between morphē and eidos—between form as irreducibly immanent and yet somehow separate—is then shown to animate Aristotle's phenomenological approach to the being of natural beings. This approach is most clearly enacted in Aristotle's biology, a consideration of which concludes the essay. (shrink)

This essay suggests the possibility of conceiving the transcendental synthesis of imagination in Kant's Critique of Pure Reason as the understanding at work on sensibility by developing an active conception of identity according to which the distinction between the imagination and the understanding is merely nominal. Aristotle's philosophy is shown both to provide such a conception of identity and to be tacitly at work in Kant's thinking. Finally, the essay traces this position into the discussion of aesthetic judgment in the (...) Critique of Judgment. (shrink)

Essays honoring the work of Catholic ethicist James F. Keenan.

The mad scientist stories of fiction and film are exercises in antirationalism, particularly its Gothic horror variant. As such, they convey the argument that rationalist secular science is dangerous, and their principal device for doing so is to invest the evil of science in the personality of the scientist. To understand this cultural critique of science, it is necessary to understand how the symbols of the scientist's personality are manipulated. This article argues that mad scientists become increasingly amoral as nineteenth-century (...) texts are adapted to twentieth-century films. The consequence is that this cultural critique is becoming even more severe, due to external reasons independent of the glories or the crimes of real scientists. (shrink)

This paper analyzes Leibniz’s use of analogies in both natural philosophical and metaphysical contexts. Through an examination of Leibniz’s notes on scientific methodology, I show that Leibniz explicitly recognizes the utility of analogies as heuristic tools that aid us in conceiving unfamiliar theoretical domains. I further argue that Leibniz uses the notion of a self-moving machine or automaton to help capture the activities of the immaterial soul. My account helps resist the conventional image of Leibniz as an arch-rationalist unconcerned with (...) methods of empirical discovery and contributes to ongoing discussions on the nature of immaterial substance and mind in Leibniz. (shrink)

PDZ (also called DHR or GLGF) domains are found in diverse membraneassociated proteins including members of the MAGUK family of guanylate kinase homologues, several protein phosphatases and kinases, neuronal nitric oxide synthase, and several dystrophin‐associated proteins, collectively known as syntrophins. Many PDZ domain‐containing proteins appear to be localised to highly specialised submembranous sites, suggesting their participation in cellular junction formation, receptor or channel clustering, and intracellular signalling events. PDZ domains of several MAGUKs interact with the C‐terminal polypeptides of a subset (...) of NMDA receptor subunits and/or with Shaker‐type K+ channels. Other PDZ domains have been shown to bind similar ligands of other transmembrane receptors. Recently, the crystal structures of PDZ domains, with and without ligand, have been determined. These demonstrate the mode of ligand‐binding and the structural bases for sequence conservation among diverse PDZ domains. (shrink)

As Sorcerer Supreme, Doctor Stephen Strange has had several occasions in which he had to deal with the concept of a personal God. Despite his lack of traditional faith, there are important instances in which Doctor Strange acknowledges the Creator God using expressions drawn from the Western monotheistic traditions. In his Metaphysics, the ancient Greek philosopher Aristotle presents the idea of God, or more specifically a god among the gods, who is responsible for the origin and operation of the whole (...) universe. A more helpful image of God can be found in the writing of Saint Thomas Aquinas, who formed a theological synthesis of Aristotelian philosophy and Christian revelation. According to Aquinas, the all‐good Creator of the universe is the author of the moral law. In the Chronicles of Narnia, author and English professor C. S. Lewis refers to the eternal law of God as the “deep magic” that comes from the “Emperor Beyond the Sea”. (shrink)

In March 2004, the U.K. government announced its intention to grant limited authorization for the growing of commercial genetically modified (GM) crops. This article reviews the potential liabilities that may arise from GM cropping, for environmental damage and for economic losses claimed by non-GM producers. It considers the application of the European Community (EC) Environmental Liability Directive of 2004 to genetically modified organisms (GMO) releases, and the proposed statutory scheme for the coexistence of GM and non-GM agriculture in England and (...) Wales. It also examines the application of the common law of nuisance to the release of GMOs and considers the relevant case law of the English courts. Although there will be a residual role for liability at common law following the establishment of a statutory coexistence scheme, the article highlights a number of formidable problems facing attempts to establish claims for liability arising from GMO releases at common law. (shrink)

Introduction: Although deep brain stimulation often improves levodopa-responsive gait symptoms, robust therapies for gait dysfunction from Parkinson's disease remain a major unmet need. Walking speed could represent a simple, integrated tool to assess DBS efficacy but is often not examined systematically or quantitatively during DBS programming. Here we investigate the reliability and functional significance of changes in gait by directional DBS in the subthalamic nucleus.Methods: Nineteen patients underwent unilateral subthalamic nucleus DBS surgery with an eight-contact directional lead in the most (...) severely affected hemisphere. They arrived off dopaminergic medications >12 h preoperatively and for device activation 1 month after surgery. We measured a comfortable walking speed using an instrumented walkway with DBS off and at each of 10 stimulation configurations at the midpoint of the therapeutic window. Repeated measures of ANOVA contrasted preoperative vs. maximum and minimum walking speeds across DBS configurations during device activation. Intraclass correlation coefficients examined walking speed reliability across the four trials within each DBS configuration. We also investigated whether changes in walking speed related to modification of step length vs. cadence with a one-sample t-test.Results: Mean comfortable walking speed improved significantly with DBS on vs. both DBS off and minimum speeds with DBS on. Pairwise comparisons showed no significant difference between DBS off and minimum comfortable walking speed with DBS on. Intraclass correlations were ≥0.949 within each condition. Changes in comfortable walk speed were conferred primarily by changes in step length.Conclusion: Acute assessment of walking speed is a reliable, clinically meaningful measure of gait function during DBS activation. Directional and circular unilateral subthalamic DBS in appropriate configurations elicit acute and clinically significant improvements in gait dysfunction related to PD. Next-generation directional DBS technologies have significant potential to enhance gait by individually tailoring stimulation parameters to optimize efficacy. (shrink)

This paper is an initial attempt to develop a dynamic conception of being which is not anarchic. It does this by returning to Aristotle in order to begin the process of reinterpreting the meaning of ousia, the concept according to which western ontology has been determined. Such a reinterpretation opens up the possibility of understanding the dynamic nature of ontological identity and the principles according to which this identity is established. The development of the notions of energeia, dynamis and entelecheia (...) in the middle books of Aristotle’s Metaphysics will be discussed in order to suggest that there is a dynamic ontological framework at work in Aristotle’s later writing. This framework lends insight into the dynamic structure of being itself, a structure which does justice as much to the concern for continuity through change as it does to the moment of difference. The name for this conception of identity which affirms both continuity and novelty is "legacy." This paper attempts to apprehend the meaning of being as legacy. (shrink)

Four centuries ago, Christian moral theologians addressed the issue of dying by turning to scripture and the virtues. This work revives that tradition by showing that careful theological reflection upon the nature of Christian patience, compassion, and hope illuminates the shape of the Good Death. The author draws upon Luke's passion narrative to develop a better understanding of these virtues. He also takes up the question of whether Jesus' death can be a model of dying well for contemporary Christians. Christians (...) are often advised to look to Jesus in his dying as a model for themselves, but this recommendation typically leaves unanswered what exactly it is about Jesus' dying that is to be imitated. The understanding of patience, compassion, and hope developed here provides a means of sorting through this issue. (shrink)

Dwyer's book is unique and distinctive as it presents and discusses a modern conceptualization of critical thinking – one that is commensurate with the exponential increase in the annual output of knowledge. The abilities of navigating new knowledge outputs, engaging in enquiry and constructively solving problems are not only important in academic contexts, but are also essential life skills. Specifically, the book provides a modern, detailed, accessible and integrative model of critical thinking that accounts for critical thinking sub-skills and real-world (...) applications; and is commensurate with the standards of twenty-first-century knowledge. The book provides both opportunities to learn and apply these skills through a series of exercises, as well as guidelines on how critical thinking can be developed and practised, in light of existing psychological research, which can be used to enhance the experience of critical thinking training and facilitate gains in critical thinking ability. (shrink)

A novel rereading of the relationship between ethics and ontology in Aristotle.

The original article has been corrected. Figures 1 and 2 have been replaced. During typesetting of the article, one of the five steps in section 4 was removed.

The discovery of a second genesis of life besides the one on Earth, this time on Mars, would have profound scientific and philosophical implications. Scientifically, it would provide a second example of biochemistry and of evolutionary history. Many important biological questions may be answerable through the comparison of biochemistry between the life forms on the two planets. Philosophically, the discovery of a second genesis of life in our solar system would suggest that the phenomenon of life is distributed throughout the (...) universe. We could finally be confident that we are not alone. To protect a second genesis as we search for it, the robotic and human exploration of Mars should be done in a way that is biologically reversible, i.e., we must be able to undo our contamination of Mars if we discover a second genesis of life there. It is important to note that human exploration can be done in a way that is biologically reversible. Further, the discovery of a second genesis of life on Mars poses new questions in ethics. One question is: what ethical consideration is due to an alien life form when that life is distinctly different from Earth life, and the members of that life are no more advanced than microorganisms? Will we choose to terraform Mars to enhance the richness and diversity of the indigenous life we find there? In considering our answers to these questions, we should note that for most of Earth’s history our ancestors were microscopic. (shrink)

At least since the appearance of Aristotle’s Politics, Plato’s Republic has been read as arguing for a politics of unity in which difference is understood as a threat to the polis. By focusing on the musical imagery of the Republic, and specifically on its compositional organization around three ‘preludes’, this essay seeks an understanding of Socratic politics that moves beyond the hypothesis of unity. In the first ‘prelude’, Thrasymachus and his insistence that justice is the self-interest of the stronger threatens (...) to subject the harmony of the community to the tyrannical whims of the individual. In the second, the perfected justice of Adeimantus’s city threatens to destroy the erotic rhythm of difference that is the very condition for the possibility of the polis. It is only in the song of dialectic, which itself is called a ‘prelude’, that the tension between the rhythm of plurality and the rational homophony of unity is dynamically tuned in such a way that both the anarchic politics of self-interest and the totalitarian politics of rationalized oppression are equally muted. This conception of politics is embodied in the relationship that emerges between Glaucon and Socrates. Ultimately, the true political community is established here, between rational, erotic individuals seeking justice in concrete, living dialogue. (shrink)

This essay articulates the differences and suggests the similarities between the practices of Socratic political speaking and those of Platonic political writing. The essay delineates Socratic speaking and Platonic writing as both erotically oriented toward ideals capable of transforming the lives of individuals and their relationships with one another. Besides it shows that in the Protagoras the practices of Socratic political speaking are concerned less with Protagoras than with the individual young man, Hippocrates. In the Phaedo, this ideal of a (...) Socrates is amplified in such a way that Platonic writing itself emerges as capable of doing with readers what Socratic speaking did with those he encountered. Socrates is the Platonic political ideal. The result is a picture of the transformative political power of Socratic speaking and Platonic writing both. El ensayo articula diferencias y sugiere similitudes entre las prácticas del diálogo político de Sócrates y aquellas de la escritura política de Platón. Propone, además, que tanto el diálogo socrático como la escritura platónica se orientan eróticamente hacia ideales capaces de transformar las vidas de los individuos y sus relaciones. Demuestra que en el Protágoras las prácticas del diálogo socrático se ocupan menos de Protágoras que del joven Hipócrates. En el Fedón, este ideal de Sócrates se amplía de tal manera que la misma escritura platónica aparece como capaz de hacer con los lectores lo que el diálogo de Sócrates hacía con sus interlocutores. Sócrates es el ideal político platónico. El resultado es una visión del poder de transformación política tanto del diálogo socrático como de la escritura platónica. (shrink)